Precision oncology
See it. Treat it.
Using targeted radiation to combine therapeutic and diagnostic modalities, Telix’s technology has potential to benefit patients across their entire medical journey. Our broad and deep portfolio and innovative pipeline are supporting clinicians to make the best decisions, more accurately and efficiently, and to deliver better patient outcomes – quality and quantity of life.
Targeted radiation
Many existing therapies for cancer and rare diseases are non-selective and as a result can act against healthy tissue and vital organs while treating disease. Existing external beam radiation therapy (EBRT) approaches are effective but typically only deliver localised treatment and cause damage to surrounding tissue. Localised therapeutic approaches rely on the treating physician making assumptions about the extent of disease and can result in imprecise application of treatment. Treatments that miss small amounts of affected cells can lead to a recurrence of the cancer or disease.
Our radiopharmaceuticals are designed to deliver focused doses of radiation with precision targeting via an injection, regardless of where the cancer or disease is in the body.
How does targeted radiation work?
Targeted radiation drug
A radioactive isotope (‘payload’) is attached to a targeting agent such as a small molecule or antibody, with an affinity for biomarkers found on the surface of cancerous or diseased cells.
Depending on the choice of radioisotope payload, either imaging or therapy can be delivered.
Intravenous injection
The targeted radiation drug is administered into the bloodstream and circulates throughout the body.
Targeted delivery
Targeted radiation seeks out cancerous or diseased cells wherever they are, including small metastases (where the cancer has spread) and binds selectively to its target.
The specificity of the targeting agent is designed to concentrate radiation at the tumour sites and to limit off-target tissue exposure. This is different from traditional radiation therapy, which is typically only delivered to a local tumour site.
See it. Treat it.
Some radioisotopes have physical properties that may be used to image cancer or rare diseases, for diagnosis and staging purposes.
Higher dose radiation with different alpha- and beta-emitting radioisotopes can be used as therapies to kill cancerous or diseased cells.