Telix at ASCO GU 2023
10 February 2023
ASCO GU (February 16-18, 2023), the leading specialised event for GU cancer care worldwide, will be the forum at which the Company will present results of the Phase III ZIRCON study (ClinicalTrials.gov Identifier: NCT03849118) of TLX250-CDx (89Zr-DFO-girentuximab) in clear cell renal cell carcinoma (ccRCC).
The program will also include six presentations on Telix’s carbonic anhydrase IX (CAIX)- and prostate specific membrane antigen (PSMA)-targeting theranostic candidates. Presentations will report on advancements in positron emission tomography (PET) imaging of prostate cancer with 68Ga PSMA-11; the potential utility of TLX250-CDx in tumour types beyond ccRCC; and the STARLITE Phase II studies, which are assessing the efficacy of TLX250 (177Lu-DOTA-girentuximab) targeted radiation in combination with immunotherapy for ccRCC.
ASCO GU presentation details are as follows:
Session: Oral Abstract Session C: Renal and Rare Tumors
Title: Results from phase 3 study of 89Zr-DFO-girentuximab for PET/CT imaging of clear cell renal cell carcinoma (ZIRCON)
Date and Time: 18-Feb-2023, 2:00 PM-3:30 PM
Presenter: Brian Shuch (UCLA)
Abstract ID: LBA602
Poster Session B: Prostate Cancer and Urothelial Carcinoma
Date and Time: 17-Feb-2023, 12:30 PM-2:00 PM & 5:15 PM-6:15 PM
Title: “68Ga-PSMA-11 patients with newly diagnosed and recurrent prostate cancer (Firefly Study) – Preliminary Results.”
Presenter: Bradley, Olivia (Tulane Cancer Center); senior author: Oliver Sartor (Tulane Cancer Center)
Abstract ID: 54
ClinicalTrials.gov Identifier: NCT04854369
Title: “Ga-68 PSMA-11 (Illuccix) impacting prostate cancer management in a real-world setting: a pilot experience using the total-body PET/CT scanner (uExplorer).”
Presenter: Hashad Kulkarni (BAMF Health)
Abstract ID: 62
Trials in Progress Poster Session C: Renal Cell Cancer; Adrenal, Penile, Urethral, and Testicular Cancers
Date and Time: 18-Feb-23, 07:00 AM-08:00 AM & 12:30 PM-2:00 PM
Title: “89Zr-DFO-girentuximab for PET imaging of solid tumors likely to express high levels of carbonic anhydrase IX” (STARBURST study)”
Presenter: Amol Talkalkar (Emory)
Abstract ID: TPS738
ClinicalTrials.gov Identifier: NCT05563272
Title: “Phase 1b/2 study of combination 177Lu girentuximab plus cabozantinib and nivolumab in treatment naïve patients with advanced clear cell RCC” (STARLITE 1 study)
Presenter: Elshad Hasanov (MD Anderson Cancer Center)
Abstract ID: TPS749
Title: “Phase 2 Study of Nivolumab plus 177Lutetium-labeled Anti–Carbonic Anhydrase IX (CAIX) Monoclonal Antibody Girentuximab (177Lu-girentuximab) in Patients (pts) with Advanced Clear Cell Renal Cell Carcinoma (ccRCC)” (STARLITE 2 study)
Presenter: Darren Feldman (Memorial Sloan Kettering Cancer Center)
Abstract ID: TPS752
ClinicalTrials.gov Identifier: NCT05239533